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  • on atoms are unsubstituted with other than H or at least 1 non-bridging ring carbon atom is substituted with R20 or ???O; [0189] or Z is taken together with A to form an aryl ring structure comprising 6 ring atoms wherein the aryl ring carbon atoms are unsubstituted with other than H or at least 1 non-bridging ring carbon atom is substituted with R6 or ???O; [0190] R6 is independently H, C1-6 alky
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