osed to higher levels of repaglinide (118).Furthermore, Dai et al. (119) found that rs2237892 (C>T) and rs2237895 (C>A) SNPs, both located in intron 15 of KCNQ1 gene (120), encoding a voltage-gated K+channel expressed in the various tissues including pancreas, were associated with the repaglinide efficacy in Chinese T2DM patients.