It is not known if bupropion hydrochloride extended-release tablets (SR) can harm your baby. have liver problems, especially cirrhosis of the liver. have kidney problems. have an eating disorder such as anorexia nervosa or bulimia. have had a head injury. have had a seizure (convulsion, fit). have a tumor in your nervous system (brain or spine). have had a heart attack, heart problems, or high blo