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  • It is most commonly idiopathic but may also be due to mumps, oophoritis, irradiation or chemotherapy. -It can be associated with disorders such as Hashimoto's thyroiditis, Addison's disease, type I diabetes mellitus and pernicious anemia, which supports the hypothesis of an autoimmune origin. -Diagnosis is confirmed by increased FSH serum levels and in patients less than 30 years. -A chromosomal a
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