In some embodiments, the 19-nor vitamin D analog administered to the subject or used to prepare a pharmaceutical formulation is a compound of formula IIO where R1 is a ???ydroxyl-substituted branched chain alkyl group having 6 carbon atoms (a ???CH2CH2CH2C(CH3)2OH group), R2 and R3 are a group of formula IC, R4 is H, R5 is a hydroxypropyl group, and the compound has the name 2-(3???-hydroxypropyli