In some embodiments, the 19-nor vitamin D analog administered to the subject or used to prepare a pharmaceutical formulation is a compound of formula IIQ where R1 is a ???ydroxyl-substituted branched chain alkyl group having 6 carbon atoms (a ???CH2CH2CH2C(CH3)2OH group), R2 and R3 are a group of formula IC, R4 is H, R5 is a ???CH2CH2OCH2OCH3 group (a protected hydroxyalkyl group), and the compoun