The CDK6 gene is conserved in eukaryotes, including the budding yeast and the nematode Caenorhabditis elegans.[7] The CDK6 gene is located in the chromosome 7 in humans, it is encoded by 231,706 base pairs and is translated to a 326 amino acid protein with a kinase function.[2] The gene is over expressed in cancers like lymphoma, leukemia, medulloblastoma and melanoma associated with chromosomal r