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  • Chem. 2004, 47(3), 627 and U.S. Pat. No. 6,476,060.##STR00006## In compound AA, one of X, Y, X', Y', X'', Y, Z, Z', or Q is a group capable of reducing or limiting the CNS activity of compound AA. This reduced or limited CNS activity occurs via at least one of X, Y, X', Y', X'', Y, Z, Z', and Qbeing a group that either limits compound AA's ability to cross the BBB relative to that of SLV319 or ena
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