le with breathingtrouble with sleepinguncomfortable swelling around the anusunpleasant breath odorunusual tiredness or weaknessunusual weight gain or lossvomitingvomiting of bloodwhite patches in the mouth, tongue, or throatwrinkled skinyellow eyes or skinLess commonBone or skeletal painburning, numbness, pain, or tingling in all fingers except smallest fingerchest paindepressed mooddry skin and h