Official URL: <a href="http://dx.doi.org/10.1016/s0965-1748(03)00064-x">http://dx.doi.org/10.1016/s0965-1748(03)00064-x</a> Abstract Insecticide resistance in laboratory selected Drosophila strains has been associated with upregulation of a range of different cytochrome P450s, however in recent field isolates of D. melanogaster resistance to DDT and other compounds is conferred by one P450 gene, Cyp6g1.