creased knee adduction moment or KAM due to varus malalignment in medial knee OA), obesity, muscle weakness, sarcopenia, systemic and local inflammation, sedentariness, and dietary intake of fat, antioxidants and other micronutrients alter the risk and progression of OA.Elevated KAM has been shown to increase the risk of radiographic medial knee OA progression by 6.5-fold, more than any other char