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During wound healing, migrating cells, such as smooth muscle cells (SMC), endothelial cells and keratinocytes, exhibit an increased expression of the vitronectin receptor (VNR) integrins including ??V ??3 and ??V ??5 (Liaw, L. et al., J Clin Invest 95:713-724 (1995); Liaw et al., Circ Res 77:665-672 (1995); Brooks et al., 1994, supra; Brooks, P. C. et al., Cell 79:1157-1164 (1994)).
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