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The compounds, including ML-236B (wherein R1 is 1-methylpropyl, R2 is hydrogen and R3 is a methyl group) and its derivatives, may be isolated and purified from fungi as known in the art and as shown in U.S. Pat. Nos. 3,983,140; 4,049,495; 4,231,938; 4,346,227; and 4,432,996 which are hereby incorporated by reference in their entirety.
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