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It has therefore been recommended as standard practice for adult ventilated patients.55,56 These 'sedation vacations' are not appropriate for children and infants as the PICU is a foreign and frightening environment for a non-sedated child, inadequate sedation is a risk factor for accidental extubation,57 and re-intubation increases the risk of VAP.7 Paediatric studies suggest that children are be
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