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Examples of bioactive polypeptides include, but are not limited to, various types of antibodies, cytokines (e.g., IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-10, IL-12, IL-15, IFN-??, IFN-??, and IFN-??), cell adhesion molecules (e.g., CTLA4, CD2, and CD28), ligands (e.g., TNF-??,, TNF-??, and an anti-angiogenic factor such as endostatin), receptors, a
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