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Exploring some of these questionsusing the powerful genetic tools of C. elegans may have im-plications for our understanding of not only FOXO biologybut also age-associated diseases such as cancer and diabetes.AcknowledgmentsH.A.T. is a William Randolph Hearst Young Investigator.This publication was made possible by an endowment fromtheWilliamRandolphHearstFoundation andgrantsfromtheNIA (1R01AG025
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