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Suitable vehicles for otic administration are organic or inorganic substances, which are pharmaceutically acceptable and which do not react with the modulator specific to Group I mGluR (such as mGluR1 and/or mGluR5), for example saline, alcohols, vegetable oils, benzyl alcohols, alkylene glycols, polyethylene glycols, glycerol triacetate, gelatin, carbohydrates such as lactose or starch, magnesium
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