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Here we review theclinical manifestations associated with DAX1 mutations as well as the evolving information aboutits function based on animal models and in vitro studies.Human StudiesClinical Features of AHCX-linked AHC is a disorder that presents in infancy with adrenal insufficiency and occurs infewer than 1:12, 500 live births (Sikl, 1948, Mitchell and Rhaney, 1959, Dacou and DiGeorge, 1968, U
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