. "Moreover, brain is an organ prone to produce reactive oxidative species such as superoxide anion (O2 ???), hydrogen peroxide (H2O2), and the hydroxyl radical (OH???), because it needs a large amount of oxygen to maintain its normal function but is deficient in anti-oxidants [36].In oxidative stress, reactive oxygen species (ROS) could damage macro-molecules such as lipid and nuclear acid to genera" . . . .