"sphonooxy(C2-C24)alkyl, and ??-carboxy(C1-C24)alkyl; and Z is ???O??? or ???S???; with the proviso that when R3 is ???PO3R11R12, R4 is other than ???PO3R13R14, and further proviso that when R3 is ???PO3H2, R4 is H, R10 is H, R1 is n-tetradecanoyl, R2 is n-octadecanoyl and R5 is n-hexadecanoyl, then X is other than ???O???, providing that the compound is other than monophosphoryl lipid A or 3-deacy" . . . .