. "th a sequence such as defined in a), b) or c); [0067] e) a nucleotide sequence comprising a sequence such as defined in a), b), c) or d); and [0068] f) a nucleotide sequence modified by a nucleotide sequence such as defined in a), b), c), d) or e). [0069] Nucleotide, polynucleotide or nucleic acid sequence will be understood according to the present invention as meaning both a double-stranded or s" . . .