. . "X is O; Z is NO2, CN, COR, or CONHR; Y is I, CF3, Br, Cl, F or Sn(R)3; R is an alkyl group or OH; and Q is CN. In one embodiment, the invention provides a selective androgen receptor modulator (SARM) compound or its prodrug, analog, isomer, metabolite, derivative, pharmaceutically acceptable salt, pharmaceutical product, polymorph, crystal, impurity, N-oxide, hydrate or any combination thereof, re" . . . . . .