"Introduction Irritable Bowel Syndrome (IBS), the most frequent diagnosis made by gastroenterologists, is characterized by abdominal pain, and altered bowel habits, including diarrhea, constipation, or both. [1],[2],[3],[4],[5],[6],[7] IBS affects individuals of all ages, comprising 40% of outpatient consultations and estimated to affect 25-45 million patients in the United States. [8] The prevalen" . . . . .