"In particular, the proinflammatory cytokines such as tumor necrosis factor (TNF)-??, interleukin (IL)-1, and IL-6 and the pro-inflammatory enzymes including inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 have been widely accepted with involvement of promoting inflammatory processes [8, 9].In this study, we investigated the effects of the ethanol extract of L. japonica (LJE) as a" . . . . .