"The size and stability of the nanoparticles depended on factors such as medium pH, concentration and ratio of ??-poly (glutamic acid) and chitosan solutions as well as the mixing order [53].In a study wherein chitosan-??-poly (glutamic acid) polyelectrolyte complex nanoparticles were investigated as drug carriers for targeted drug delivery, it was shown that they can penetrate A2780/AD ovarian can" . . . . .