. . . "hat is the connection between intrinsic factor, viatmin B12 and the pancreas in cats? the pancreas secretes intrinsic factor which is essential for the absorption of vitamin B12, if EPI causes a decrease in IF, you should also see a decreases in B12 ??? ??? ??? Where organ system other than the pancreas can you have intrinsic factor secretion. the stomach secretes IF ??? ??? ??? What will you susp" .