. "It occurs most often in men ages 50 to 70.The exact cause is unknown.The following may increase your risk of kidney cancer:Dialysis treatmentFamily history of the diseaseHigh blood pressureHorseshoe kidneyPolycystic kidney diseaseSmokingVon Hippel-Lindau disease (a hereditary disease that affects blood vessels in the brain, eyes, and other body parts) Symptoms" . . . .