. "Lastly, Purdue et al. assessed the significance of age, gender, and risk factors, such as body mass index, smoking status and history of diagnosed hypertension, and saw that men had a slightly higher EPAS1-related risk of RCC. Additionally, the authors also observed that both former and current smokers carrying variants of EPAS1 seemed to be at greater risk of RCC than non-smokers, which further h" . . . . .