You may be able to access a copy if URLs are provided below. (Contact Author) Official URL: <a href="http://dx.doi.org/10.1002/syn.21541">http://dx.doi.org/10.1002/syn.21541</a> Abstract The density of the Imidazoline 2 binding site (I 2BS) has been shown to change in psychiatric conditions such as depression and addiction, along with neurodegenerative disorders such as Alzheimer's disease and Huntington's chorea.