ogical studies (case-control and cohort design) have demonstrated an association between use of drugs that interfere with serotonin reuptake and the occurrence of gastrointestinal bleeding.Patients should be cautioned about the risk of bleeding associated with the concomitant use of ZOLOFT and NSAIDs, aspirin, or other drugs that affect coagulation.Weak Uricosuric EffectZOLOFT (sertraline hydrochl