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  • For example, the salts can be prepared by reacting the free base with the appropriate acid in water or in an organic solvent, or in a mixture of the two; generally, nonaqueous media such as ether, ethyl acetate, methanol, ethanol, isopropanol, or acetonitrile are used.In another aspect, the invention provides a method of preparing an acid addition salt of 1-(2,6-difluorophenyl)-N-[3-(5-morpholin-4
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