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  • o adjust to the backbone hydrogen bonding pattern of A??16-20m and, thereby, facilitate the formation of an inhibitor-A??1-40 complex, while two or more molecules of A??16-20m are too rigid to conform to each other and form an aggregate. [0100] A??16-20m was found to be highly soluble not only in aqueous media but also in organic solvents such as dimethylformamide, dichloromethane, and even diethy
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