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  • For example, when the polypeptide is a netrin polypeptide or an agent that promotes the expression or activity of a netrin polypeptide or of netrin signaling, exemplary biological activities retained by a modified polypeptide for use in the methods of the present invention include one or more of the following: (i) binds a netrin receptor; (ii) promotes attraction of axons; (iii) promote angiogenes
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