For instance, regulatory mechanisms for Rheb and TOR discovered in animals, such as in D. melanogaster do not necessarily hold for C. elegans and vice versa.Translationally Controlled Tumor Protein 1, No Phylogenetic Linkage with Rheb TCTP (also known as TPT1) has been reported to be the Guanine Exchange Factor (GEF) for Rheb (Hsu et al. 2007) but this function has been debated by us and others (R