To understand the impact hypoxia has on the developing brain, the most prominent types of brain injury are described below.Preterm brain injury Premature neonates who are also of a low birth weight are at the highest risk of PVL and GM-IVH. The source of GM-IVH was classified by Takashima and Tanaka (1978b), Wigglesworth and Pape (1978), and Volpe (1989) who described bleeding occurring around the