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  • H--) or b is 2 to 20 (when M is --O--); c is 1 or 2; Z is oxygen or NH2 + ; and W is hydrogen or --NHC(???O)--R' where R' is an alkyl group having 1 to 6 carbon atoms; ##STR36## formed from coupling the reactive carbon center-derivatized support of Equation 5 and the thiol-derivatized oligonucleotide of Equation 13 (when M is --NH--) or Equation 15 (when M is --O--) and wherein M is --NH-- or oxyg
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