ovsky And Popeo, P.c20110028475 - Tetrahydroisoquinoline sulfonamide derivatives, the preparation thereof, and the use of the same in therapeutics: wherein R1, R2, n and B are as defined in the disclosure, their preparation and their use in therapies for the treatment of central nervous system diseases such as vigilance and sleep disorders, narcolepsy, Alzheimer's disease and other dementias, Park