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  • ous insufficiency; varicose therapy; hemorrhoids; and shock states associated with amarked drop in arterial pressure (e.g. septic shock).Compounds of the invention are also useful in the treatment of neurodegenerative diseases and neurodegeneration such as dementia, particularly degenerative dementia (including senile dementia, Alzheimer's disease, Pick's disease, Huntingdon'schores, Parkinson's d
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