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  • Preferably, address probes are coupled, either directly or via a spacer molecule, to a solid-state substrate or support. [0197] N. Nucleic Acids [0198] The disclosed methods and compositions use and involve nucleic acids, including, for example, base nucleic acids, manipulated product nucleic acids, mRNA, cDNA, primers, probes, amplification target circles, and other oligonucleotides.
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