The 12-month efficacy of the doxycycline treatment was 97% (67 of 69 treated individuals), compared with the untreated group with 16% (10 of 63) and with the ivermectin/albendazole group with 19% (5 of 27) [59].Adverse effects include fever, headache, itching, myalgia, which is high in particular in regions such as Cameroon where L. loa is endemic simultaneously.