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  • serts are isolated on a preparative gel, purified, and ligated to form an insert spanning therange of the two source inserts.VI. Diagnostic ApplicationsThe Spry proteins and coding sequences have utility in detecting (i) the presence or absence of mutations in a Spry gene, and (ii) the level of Spry proteins present in a given tissue or organ, including a solid tumor present as a primary orseconda
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