As used herein, a promoter is a substance which promotes (induces or enhances) at least one function characteristic of a mammalian C???C chemokine receptor (e.g., a mammalian CKR-3 receptor), such as a binding activity (e.g., ligand, inhibitor and/or promoter binding), a signalling activity (e.g., activation of a mammalian G protein, induction of rapid and transient increase in the concentration o