Usually, signs begin to show between the ages of 4 to 8.Signs of Fabry include:Episodes of pain, particularly in hands and feet (???Fabry crises???)Small, dark red spots on skin (angiokeratomas)Loss of ability to sweat (hypohidrosis)Cloudiness in front part of eyes (corneal opacity)Hearing lossDifficulty gaining weightStomach pain, nausea, and vomitingUnknown cause of kidney failureHeart murmur (a