FIG. 2 is a schematic of the method of the present invention used to micropattern biotin-amine onto PET. The lower left panel is a 20???magnification confocal image of Alexa??? 488-labeled streptavidin (0.1 ??M in HBS, pH 7.4) bound to biotin-amine, which was patterned onto PET-COOH using techniques described herein.