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  • Thought not particularly restricted, the freeze-drying time is generally about 24 to 72 hours. (4) Cross-Linking of Collagen The cross-linking of collagen may be carried out by any methods such as physical cross-linking methods using ??-rays, ultraviolet rays, electron beams, thermal dehydration, etc., or chemical cross-linking methods using cross-linking agents, condensation agents, etc.
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