I love it to pieces and have been on it a few times over the years, only problem is it comes in at a whopping 140$, canada 70$ a tube, on the internet it looks like there is a generic but I do not think it exists in the u.s. works for both male and females.even using this alone would show good results I think.4.tretinoin: .025% 38$ lasts 2-3 months , canada 16-20$ I think.and was aplied at night.