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  • The discovery of vitamin A may have stemmed from research dating back to 1816, when physiologist Fran??ois Magendie observed that dogs deprived of nutrition developed corneal ulcers and had a high mortality rate.[9] In 1912, Frederick Gowland Hopkins demonstrated that unknown accessory factors found in milk, other than carbohydrates, proteins, and fats were necessary for growth in rats.
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