wherein: A is ???C(???O)R, where R is aliphatic, aromatic, alicyclic or heterocyclic having from 1 to 8 carbon atoms and 0 to 4 heteroatoms selected from the group consisting of O, S. and N; ???CH2-???C(???O)???NH???CHO; ???SO2H; ???CH2???C(???O)O???CHO; ???C(???O)NH???(CH2)n???NH???C(???O)C(???O)???(C6H5), where n is in the range of from 2 to 12; D is a detection moiety; and M is a bond or an org