features of the metabolic syndrome including dyslipidemia, insulin resistance, and hypertension [15???17, 18???]; 2) a mutated form of Ogn (osteoglycin) has been confirmed as a gene predisposing to cardiac hypertrophy [19???]; and 3) a variant in Srebf1 (sterol regulatory element binding factor 1c isoform) has been confirmed to exert effects on hepatic lipid levels [20].