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  • However, reversal can be difficult for drugs associated with addiction, such as narcotics and alcohol, and at times, these effects can be fatal, as with hypoglycemic coma induced by insulin.5,6 Harmful effects that are unrelated to the principal action of the drug are rare. 5,6 Unusual and unpredictable responses to medications, such as anaphylaxis, are referred to as idiosyncratic reactions.
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